Gleolan (aminolevulinic acid HCl) is the first and only FDA approved optical imaging agent for use during fluorescence-guided surgery (FGS) in patients with glioma [suspected World Health Organization (WHO) Grades III or IV on preoperative imaging] as an adjunct for the visualization of malignant tissue during surgery. Aminolevulinic acid HCl has been used in over 42 countries for over 80,000 patients1.

REFERENCES
1. Data on File, NX Development Corp.

FGS

About Gleolan

Gleolan is the first and only FDA approved optical imaging agent for use during fluorescence-guided surgery in patients with glioma [suspected World Health Organization (WHO) Grades III or IV on preoperative imaging] as an adjunct for the visualization of malignant tissue during surgery.

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Patient information

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Q: What is Gleolan for?
Gleolan is known as an “imaging agent” that is taken by patients before surgery to help neurosurgeons to see certain brain tumors, known as “high-grade gliomas”.

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Patient Safety Information

Gleolan can cause a sunburn-type skin reaction, also referred to as photosensitivity. Do not take any drugs that may worsen this (such as St. John’s wort, griseofulvin, thiazide diuretics, sulfonylureas, phenothiazines, sulphonamides, quinolones, and tetracyclines) and do not put anything on your skin that contains aminolevulinic acid (ALA) for 24 hours before and for 24 hours after receiving Gleolan.

Errors may occur with the use of Gleolan to see tumors. Sometimes brain tumor cells may fluoresce even if they are not cancerous or those that are cancerous my not fluoresce. Also, cancer cells from other tumors or areas of swelling may fluoresce.

Allergic reactions, including serious allergic reactions, to Gleolan have occurred. Your medical team should monitor you for this and should have emergency equipment ready to manage any such reaction if it occurs.

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Patient Safety Information

Gleolan can cause a sunburn-type skin reaction, also referred to as photosensitivity. Do not take any drugs that may worsen this (such as St. John’s wort, griseofulvin, thiazide diuretics, sulfonylureas, phenothiazines, sulphonamides, quinolones, and tetracyclines) and do not put anything on your skin that contains aminolevulinic acid (ALA) for 24 hours before and for 24 hours after receiving Gleolan.